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6S Evidence-Based Clinical Resources

This guide is intended to help the busy clinician find the best evidence quickly using a hierarchy of content by levels of evidence.

Summaries

“The next best step is to look for summaries. These include clinical pathways or textbook summaries…. Evidence-based, current clinical practice guidelines… are also examples of “summary” level evidence.” (DiCenso)

CMA InfoBase: Clinical Practice Guidelines  

  • Database of CPGs developed or endorsed by authoritative medical or health organizations in Canada

DynaMed Plus  

  • Point of care, evidence based clinical summaries on over 3000 topics
  • Monitors over 500 journals & systematic evidence review sources with new evidence integrated daily

First Consult  

  • Continuously updated, evidence-based content aimed at primary care providers
  • Part of Elsevier’s ClinicalKey – change drop-down from “All Types” to “First Consult”

LactMed 

  • Information on drugs and other chemicals to which breastfeeding mothers may be exposed
  • Includes information on possible adverse effects of levels in breast milk and infant blood 
  • Also suggests therapeutic alternatives when appropriate

National Guideline Clearinghouse 

  • A comprehensive, international collection of evidence-based clinical practice guidelines

Natural Medicines (formerly Natural Standard and Natural Medicine Comprehensive Database)  

  • Summarizes & grades (from “strong evidence” through “strong negative evidence”) for foods, herbs, supplements and non-herbal modalities such as acupuncture.
  • Can also be searched for CAM interventions by disease or condition
  • Includes information on drug interactions and contraindications

OrthoEvidence  

  • OrthoEvidence is a global orthopaedic-focused evidence-based summary provider built for the orthopaedic community by orthopaedic experts. Their CoreView presents critical topics in musculoskeletal research, highlighting and graphically summarizing evidence from their database of ACE reports.

UpToDate  

  • Regularly updated texts to answer clinical questions about patient care, diagnosis and treatment
  • Focuses on internal medicine and subspecialties

VisualDX  

  • A diagnostic decision support system designed by clinicians to aid medical professionals in the diagnosis of visually identifiable diseases
  • Includes more than 18,000 images representing over 1,000 diseases, drug reactions, and infections
  • Mobile access requires an internet connection

  Canadian  |   freely available  |   mobile app  |   U of C licensed