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6S Evidence-Based Clinical Resources

This guide is intended to help the busy clinician find the best evidence quickly using a hierarchy of content by levels of evidence.

Synopses of Syntheses

“When a summary does not exist for a clinical problem, then synopses of syntheses are the next best source.” (DiCenso)

CADTH (Canadian Agency for Drugs and Technologies in Health)  

  • Database of content from Canadian HTA (Health Technology Assessment) producers

EBM Reviews - ACP Journal Club (OVID) 

  • Distilled abstracts and commentaries on selected clinically relevant original studies and systematic reviews
  • Covers primary care internal medicine, hospital medicine, and subspecialties of internal medicine

EBM Reviews - Database of Abstracts of Reviews of Effects (OVID) 
Database of Abstracts of Reviews of Effects (DARE) 

  • Critical summaries of selected systematic reviews about the effects of interventions

Evidence-Based Medicine  
Evidence-Based Medicine   content free after one year

  • BMJ journal summarizing selected systematic reviews and primary studies as structured abstracts with accompanying commentaries on clinical applicability of study findings


  • OrthoEvidence is a global orthopaedic-focused evidence-based summary provider built for the orthopaedic community by orthopaedic experts.

  Canadian  |   freely available  |   U of C licensed  


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